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Nucleic acid–induced dimerization of HIV-1 Gag protein

HIV-1 Gag is a highly flexible multidomain protein that forms the protein lattice of the immature HIV-1 virion. In vitro, it reversibly dimerizes, but in the presence of nucleic acids (NAs), it spontaneously assembles into virus-like particles (VLPs). High-resolution structures have revealed intrica...

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書目詳細資料
發表在:J Biol Chem
Main Authors: Zhao, Huaying, Datta, Siddhartha A. K., Kim, Sung H., To, Samuel C., Chaturvedi, Sumit K., Rein, Alan, Schuck, Peter
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851336/
https://ncbi.nlm.nih.gov/pubmed/31570521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010580
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