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Fundamental differences between the nucleic acid chaperone activities of HIV-1 nucleocapsid protein and Gag or Gag-derived proteins: Biological implications

The HIV-1 Gag polyprotein precursor has multiple domains including nucleocapsid (NC). Although mature NC and NC embedded in Gag are nucleic acid chaperones (proteins that remodel nucleic acid structure), few studies include detailed analysis of the chaperone activity of partially processed Gag prote...

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Détails bibliographiques
Auteurs principaux: Wu, Tiyun, Datta, Siddhartha A.K., Mitra, Mithun, Gorelick, Robert J., Rein, Alan, Levin, Judith G.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963451/
https://ncbi.nlm.nih.gov/pubmed/20655566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.06.042
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