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Fundamental differences between the nucleic acid chaperone activities of HIV-1 nucleocapsid protein and Gag or Gag-derived proteins: Biological implications

The HIV-1 Gag polyprotein precursor has multiple domains including nucleocapsid (NC). Although mature NC and NC embedded in Gag are nucleic acid chaperones (proteins that remodel nucleic acid structure), few studies include detailed analysis of the chaperone activity of partially processed Gag prote...

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Detalhes bibliográficos
Main Authors: Wu, Tiyun, Datta, Siddhartha A.K., Mitra, Mithun, Gorelick, Robert J., Rein, Alan, Levin, Judith G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963451/
https://ncbi.nlm.nih.gov/pubmed/20655566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.06.042
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