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BRET-monitoring of the dynamic changes of inositol lipid pools in living cells reveals a PKC-dependent PtdIns4P increase upon EGF and M3 receptor activation

Deciphering many roles played by inositol lipids in signal transduction and membrane function demands experimental approaches that can detect their dynamic accumulation with subcellular accuracy and exquisite sensitivity. The former criterion is met by imaging of fluorescence biosensors in living ce...

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Bibliographische Detailangaben
Veröffentlicht in:Biochim Biophys Acta
Hauptverfasser: Tóth, József T., Gulyás, Gergő, Tóth, Dániel J., Balla, András, Hammond, Gerald R. V., Hunyady, László, Balla, Tamás, Várnai, Péter
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733596/
https://ncbi.nlm.nih.gov/pubmed/26692031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2015.12.005
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