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Targeted expression of the inositol 1,4,5-triphosphate receptor (IP(3)R) ligand-binding domain releases Ca(2+) via endogenous IP(3)R channels
Virtually all functions of a cell are influenced by cytoplasmic [Ca(2+)] increases. Inositol 1,4,5-trisphosphate receptor (IP(3)R) channels, located in the endoplasmic reticulum (ER), release Ca(2+) in response to binding of the second messenger, IP(3).IP(3)Rs thus are part of the information chain...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1142351/ https://ncbi.nlm.nih.gov/pubmed/15911776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407535102 |
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