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Activation of Na(+)/H(+) Exchanger NHE3 by Angiotensin II Is Mediated by Inositol 1,4,5-Triphosphate (IP(3)) Receptor-binding Protein Released with IP(3) (IRBIT) and Ca(2+)/Calmodulin-dependent Protein Kinase II

Angiotensin II (ANG II) stimulates renal tubular reabsorption of NaCl by targeting Na(+)/H(+) exchanger NHE3. We have shown previously that inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) plays a critical role in stimulation of NHE3 in response...

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Detalhes bibliográficos
Main Authors: He, Peijian, Klein, Janet, Yun, C. Chris
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934654/
https://ncbi.nlm.nih.gov/pubmed/20584908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.133066
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