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BRET-monitoring of the dynamic changes of inositol lipid pools in living cells reveals a PKC-dependent PtdIns4P increase upon EGF and M3 receptor activation

Deciphering many roles played by inositol lipids in signal transduction and membrane function demands experimental approaches that can detect their dynamic accumulation with subcellular accuracy and exquisite sensitivity. The former criterion is met by imaging of fluorescence biosensors in living ce...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Tóth, József T., Gulyás, Gergő, Tóth, Dániel J., Balla, András, Hammond, Gerald R. V., Hunyady, László, Balla, Tamás, Várnai, Péter
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733596/
https://ncbi.nlm.nih.gov/pubmed/26692031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2015.12.005
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