Lack of hepcidin expression attenuates steatosis and causes fibrosis in the liver

AIM: To investigate the role of key iron-regulatory protein, hepcidin in non-alcoholic fatty liver disease (NAFLD). METHODS: Hepcidin (Hamp1) knockout and floxed control mice were administered a high fat and high sucrose (HFS) or a regular control diet for 3 or 7 mo. Steatosis, triglycerides, fibros...

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Udgivet i:World J Hepatol
Main Authors: Lu, Sizhao, Bennett, Robert G, Kharbanda, Kusum K, Harrison-Findik, Duygu Dee
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Inc 2016
Fag:
Basic Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733464/
https://ncbi.nlm.nih.gov/pubmed/26855692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4254/wjh.v8.i4.211
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