A Meningococcal NOMV-FHbp Vaccine for Africa Elicits Broader Serum Bactericidal Antibody Responses Against Serogroup B and non-B Strains than a Licensed Serogroup B Vaccine

BACKGROUND: Meningococcal epidemics in Sub-Sahara caused by serogroup A strains are controlled by a group A polysaccharide conjugate vaccine. Strains with serogroups C, W and X continue to cause epidemics. Protein antigens in licensed serogroup B vaccines are shared among serogroup B and non-B strai...

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Veröffentlicht in:Vaccine
Hauptverfasser: Pajon, Rolando, Lujan, Eduardo, Granoff, Dan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733268/
https://ncbi.nlm.nih.gov/pubmed/26709637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2015.12.034
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