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ST2 contributes to T-cell hyperactivation and fatal hemophagocytic lymphohistiocytosis in mice
Cytokine storm syndromes, such as familial hemophagocytic lymphohistiocytosis (FHL), are lethal disorders caused by uncontrolled, systemic immune activation. In the murine model of FHL, in which perforin-deficient (Prf1(−/−)) mice are infected with lymphocytic choriomeningitis virus (LCMV), disease...
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| Publicado no: | Blood |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731846/ https://ncbi.nlm.nih.gov/pubmed/26518437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-07-659813 |
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