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ST2 contributes to T-cell hyperactivation and fatal hemophagocytic lymphohistiocytosis in mice
Cytokine storm syndromes, such as familial hemophagocytic lymphohistiocytosis (FHL), are lethal disorders caused by uncontrolled, systemic immune activation. In the murine model of FHL, in which perforin-deficient (Prf1(−/−)) mice are infected with lymphocytic choriomeningitis virus (LCMV), disease...
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| Vydáno v: | Blood |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731846/ https://ncbi.nlm.nih.gov/pubmed/26518437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-07-659813 |
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