The non-Geldanamycin Hsp90 inhibitors enhanced the antifungal activity of fluconazole

The molecular chaperone heat shock protein 90 (Hsp90) is highly conserved in eukaryotes and facilitates the correct folding, productive assembly and maturation of a diverse cellular proteins. In fungi, especially the most prevalent human fungal pathogen Candida albicans, Hsp90 influences development...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Transl Res
Hauptverfasser: Li, Liping, An, Maomao, Shen, Hui, Huang, Xin, Yao, Xueya, Liu, Jian, Zhu, Fang, Zhang, Shiqun, Chen, Simin, He, Lijuan, Zhang, Jundong, Zou, Zui, Jiang, Yuanying
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731659/
https://ncbi.nlm.nih.gov/pubmed/26885259
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