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Progesterone receptor structure and function altered by geldanamycin, an hsp90-binding agent.

The assembly of progesterone receptor (PR) heterocomplexes in vitro involves at least eight components of the molecular chaperone machinery, and as earlier reports have shown, these proteins exhibit complex, dynamic, but ordered, interactions with one another and PR. Using the selective hsp90 bindin...

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Detalhes bibliográficos
Main Authors: Smith, D F, Whitesell, L, Nair, S C, Chen, S, Prapapanich, V, Rimerman, R A
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC230934/
https://ncbi.nlm.nih.gov/pubmed/8524246
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