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A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection

A20 negatively regulates multiple inflammatory signalling pathways. We here addressed the role of A20 in club cells (also known as Clara cells) of the bronchial epithelium in their response to influenza A virus infection. Club cells provide a niche for influenza virus replication, but little is know...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Maelfait, Jonathan, Roose, Kenny, Vereecke, Lars, Mc Guire, Conor, Sze, Mozes, Schuijs, Martijn J., Willart, Monique, Itati Ibañez, Lorena, Hammad, Hamida, Lambrecht, Bart N., Beyaert, Rudi, Saelens, Xavier, van Loo, Geert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731390/
https://ncbi.nlm.nih.gov/pubmed/26815999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005410
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