Interleukin-1α controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33

House dust mite (HDM) is one of the most common allergens worldwide. In this study, we have addressed the involvement of IL-1 in the interaction between HDM and the innate immune response driven by lung epithelial cells (ECs) and dendritic cells (DCs) that leads to asthma. Mice lacking IL-1R on radi...

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Huvudupphovsmän: Willart, Monique A.M., Deswarte, Kim, Pouliot, Philippe, Braun, Harald, Beyaert, Rudi, Lambrecht, Bart N., Hammad, Hamida
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409497/
https://ncbi.nlm.nih.gov/pubmed/22802353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20112691
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