IL-33trap is a novel IL-33 neutralizing biologic that inhibits allergic airway inflammation

BACKGROUND: The emergence of IL-33 as a key molecular player in the development and propagation of widespread inflammatory diseases including asthma and atopic dermatitis has established the need for effective IL-33 neutralizing biologics. OBJECTIVE: Here we describe the development and validation o...

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Veröffentlicht in:J Allergy Clin Immunol
Hauptverfasser: Holgado, Aurora, Braun, Harald, Van Nuffel, Elien, Detry, Sammy, Schuijs, Martijn J., Deswarte, Kim, Vergote, Karl, Haegman, Mira, Baudelet, Griet, Haustraete, Jurgen, Hammad, Hamida, Lambrecht, Bart N., Savvides, Savvas N., Afonina, Inna S., Beyaert, Rudi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610802/
https://ncbi.nlm.nih.gov/pubmed/30876911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.02.028
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