IL-33trap is a novel IL-33 neutralizing biologic that inhibits allergic airway inflammation

BACKGROUND: The emergence of IL-33 as a key molecular player in the development and propagation of widespread inflammatory diseases including asthma and atopic dermatitis has established the need for effective IL-33 neutralizing biologics. OBJECTIVE: Here we describe the development and validation o...

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Publicat a:J Allergy Clin Immunol
Autors principals: Holgado, Aurora, Braun, Harald, Van Nuffel, Elien, Detry, Sammy, Schuijs, Martijn J., Deswarte, Kim, Vergote, Karl, Haegman, Mira, Baudelet, Griet, Haustraete, Jurgen, Hammad, Hamida, Lambrecht, Bart N., Savvides, Savvas N., Afonina, Inna S., Beyaert, Rudi
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610802/
https://ncbi.nlm.nih.gov/pubmed/30876911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.02.028
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