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House dust mite allergen induces asthma via TLR4 triggering of airway structural cells

Barrier epithelial cells and airway dendritic cells (DC) make up the first line of defence against inhaled substances like house dust mite (HDM) allergen and endotoxin. We hypothesized that these cells need to communicate to cause allergic disease. Using irradiated chimeric mice, we demonstrate that...

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Detalhes bibliográficos
Main Authors: HAMMAD, Hamida, CHIEPPA, Marcello, PERROS, Frederic, WILLART, Monique A., GERMAIN, Ronald N., LAMBRECHT, Bart N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789255/
https://ncbi.nlm.nih.gov/pubmed/19330007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1946
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