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House dust mite allergen induces asthma via TLR4 triggering of airway structural cells

Barrier epithelial cells and airway dendritic cells (DC) make up the first line of defence against inhaled substances like house dust mite (HDM) allergen and endotoxin. We hypothesized that these cells need to communicate to cause allergic disease. Using irradiated chimeric mice, we demonstrate that...

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書誌詳細
主要な著者: HAMMAD, Hamida, CHIEPPA, Marcello, PERROS, Frederic, WILLART, Monique A., GERMAIN, Ronald N., LAMBRECHT, Bart N.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789255/
https://ncbi.nlm.nih.gov/pubmed/19330007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1946
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