A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection

A20 negatively regulates multiple inflammatory signalling pathways. We here addressed the role of A20 in club cells (also known as Clara cells) of the bronchial epithelium in their response to influenza A virus infection. Club cells provide a niche for influenza virus replication, but little is know...

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Vydáno v:PLoS Pathog
Hlavní autoři: Maelfait, Jonathan, Roose, Kenny, Vereecke, Lars, Mc Guire, Conor, Sze, Mozes, Schuijs, Martijn J., Willart, Monique, Itati Ibañez, Lorena, Hammad, Hamida, Lambrecht, Bart N., Beyaert, Rudi, Saelens, Xavier, van Loo, Geert
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731390/
https://ncbi.nlm.nih.gov/pubmed/26815999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005410
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