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Sulfenic Acid Modification of Endothelin B Receptor is Responsible for the Benefit of a Nonsteroidal Mineralocorticoid Receptor Antagonist in Renal Ischemia

AKI is associated with high mortality rates and the development of CKD. Ischemia/reperfusion (IR) is an important cause of AKI. Unfortunately, there is no available pharmacologic approach to prevent or limit renal IR injury in common clinical practice. Renal IR is characterized by diminished nitric...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Barrera-Chimal, Jonatan, Prince, Sonia, Fadel, Fouad, El Moghrabi, Soumaya, Warnock, David G., Kolkhof, Peter, Jaisser, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731121/
https://ncbi.nlm.nih.gov/pubmed/26361797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014121216
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