Sulfenic Acid Modification of Endothelin B Receptor is Responsible for the Benefit of a Nonsteroidal Mineralocorticoid Receptor Antagonist in Renal Ischemia

AKI is associated with high mortality rates and the development of CKD. Ischemia/reperfusion (IR) is an important cause of AKI. Unfortunately, there is no available pharmacologic approach to prevent or limit renal IR injury in common clinical practice. Renal IR is characterized by diminished nitric...

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Publicat a:J Am Soc Nephrol
Autors principals: Barrera-Chimal, Jonatan, Prince, Sonia, Fadel, Fouad, El Moghrabi, Soumaya, Warnock, David G., Kolkhof, Peter, Jaisser, Frédéric
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2016
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731121/
https://ncbi.nlm.nih.gov/pubmed/26361797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014121216
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