Lupus Nephritis: Glycogen Synthase Kinase 3β Promotion of Renal Damage Through Activation of the NLRP3 Inflammasome in Lupus-Prone Mice

OBJECTIVE: Glycogen synthase kinase 3β (GSK-3β) has been demonstrated to be involved in immune and inflammatory responses via multiple signaling pathways, leading to the production of proinflammatory cytokines. The purpose of this study was to investigate the role of GSK-3β in the pathogenesis of lu...

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Udgivet i:Arthritis Rheumatol
Main Authors: Zhao, Jijun, Wang, Hongyue, Huang, Yuefang, Zhang, Hui, Wang, Shuang, Gaskin, Felicia, Yang, Niansheng, Fu, Shu Man
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731039/
https://ncbi.nlm.nih.gov/pubmed/25512114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38993
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