Podocyte Activation of NLRP3 Inflammasomes Contributes to the Development of Proteinuria in Lupus Nephritis

OBJECTIVE: Development of proteinuria in lupus nephritis (LN) is associated with podocyte dysfunction. The NLRP3 inflammasome has been implicated in the pathogenesis of LN. This study investigates whether NLRP3 inflammasome activation is involved in the development of podocyte injury in LN. METHODS:...

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書誌詳細
出版年:Arthritis Rheumatol
主要な著者: Fu, Rong, Guo, Chaohuan, Wang, Shuang, Huang, Yuefang, Jin, Ou, Hu, Haoqiang, Chen, Jingxian, Xu, Bihua, Zhou, Mianjing, Zhao, Jijun, Sung, Sun-sang J., Wang, Hongyang, Gaskin, Felicia, Yang, Niansheng, Fu, Shu-Man
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568813/
https://ncbi.nlm.nih.gov/pubmed/28544564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40155
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