Podocyte Activation of NLRP3 Inflammasomes Contributes to the Development of Proteinuria in Lupus Nephritis

OBJECTIVE: Development of proteinuria in lupus nephritis (LN) is associated with podocyte dysfunction. The NLRP3 inflammasome has been implicated in the pathogenesis of LN. This study investigates whether NLRP3 inflammasome activation is involved in the development of podocyte injury in LN. METHODS:...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Fu, Rong, Guo, Chaohuan, Wang, Shuang, Huang, Yuefang, Jin, Ou, Hu, Haoqiang, Chen, Jingxian, Xu, Bihua, Zhou, Mianjing, Zhao, Jijun, Sung, Sun-sang J., Wang, Hongyang, Gaskin, Felicia, Yang, Niansheng, Fu, Shu-Man
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568813/
https://ncbi.nlm.nih.gov/pubmed/28544564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40155
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