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Pathogenesis of Lupus Nephritis: RIP3 Dependent Necroptosis and NLRP3 Inflammasome Activation

RIP3 activation leads to activation of necroptosis and the NLRP3 inflammasome pathways. The activation of RIP3 in lupus nephritis (LN) has not been investigated. In this study, RIP3 and necroptosis pathway activations were demonstrated in podocytes in renal biopsies from patients with class IV LN an...

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Detalhes bibliográficos
Publicado no:J Autoimmun
Main Authors: Guo, Chaohuan, Fu, Rong, Zhou, Mianjing, Wang, Shuang, Huang, Yuefang, Hu, Haoqiang, Zhao, Jijun, Gaskin, Felicia, Yang, Niansheng, Fu, Shu Man
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708470/
https://ncbi.nlm.nih.gov/pubmed/31133359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2019.05.014
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