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Thioredoxin interacting protein: A novel target for neuroprotection in experimental thromboembolic stroke in mice

Redox imbalance in the brain significantly contributes to ischemic stroke pathogenesis but antioxidant therapies have failed in clinical trials. Activation of endogenous defense mechanisms may provide better protection against stroke-induced oxidative injury. TXNIP (thioredoxin-interacting protein)...

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Bibliographic Details
Published in:Mol Neurobiol
Main Authors: Ishrat, Tauheed, Mohamed, Islam N., Pharm, B., Pillai, Bindu, Soliman, Sahar, Fouda, Abdelrahman Y, Ergul, Adviye, El-Remessy, Azza B, Fagan, Susan C
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730955/
https://ncbi.nlm.nih.gov/pubmed/24939693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-014-8766-x
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