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Sequential Therapy with Minocycline and Candesartan Improves Long Term Recovery after Experimental Stroke

BACKGROUND: Minocycline and candesartan have both shown promise as candidate therapeutics in ischemic stroke, with multiple, and somewhat contrasting, molecular mechanisms. Minocycline is an anti-inflammatory, antioxidant and anti-apoptotic agent and a known inhibitor of matrix metalloproteinases (M...

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Detalhes bibliográficos
Publicado no:Transl Stroke Res
Main Authors: Soliman, Sahar, Ishrat, Tauheed, Fouda, Abdelrahman Y., Patel, Ami, Pillai, Bindu, Fagan, Susan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559761/
https://ncbi.nlm.nih.gov/pubmed/26004281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-015-0408-8
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