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Candesartan reduces the hemorrhage associated with delayed tissue plasminogen activator treatment in rat embolic stroke
We have previously reported that angiotensin receptor blockade reduces reperfusion hemorrhage in a suture occlusion model of stroke, despite increasing matrix metalloproteinase (MMP-9) activity. We hypothesized that candesartan will also decrease hemorrhage associated with delayed (6h) tissue plasmi...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3973150/ https://ncbi.nlm.nih.gov/pubmed/24194350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-013-1185-y |
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