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Candesartan reduces the hemorrhage associated with delayed tissue plasminogen activator treatment in rat embolic stroke

We have previously reported that angiotensin receptor blockade reduces reperfusion hemorrhage in a suture occlusion model of stroke, despite increasing matrix metalloproteinase (MMP-9) activity. We hypothesized that candesartan will also decrease hemorrhage associated with delayed (6h) tissue plasmi...

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Detalhes bibliográficos
Main Authors: Ishrat, Tauheed, Pillai, Bindu, Ergul, Adviye, Hafez, Sherif, Fagan, Susan C
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973150/
https://ncbi.nlm.nih.gov/pubmed/24194350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-013-1185-y
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