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PEROXYNITRITE-INDUCED TYROSINE NITRATION CONTRIBUTES TO MATRIX METALLOPROTEASE-3 ACTIVATION: RELEVANCE TO HYPERGLYCEMIC ISCHEMIC BRAIN INJURY AND TISSUE PLASMINOGEN ACTIVATOR
Matrix metalloprotease-3 (MMP3) activation mediates the tissue plasminogen activator (tPA)-induced hemorrhagic transformation (HT) after stroke. Hyperglycemia (HG) further exacerbates this outcome. We have recently shown that HG increases MMP3 activity in the brain after stroke. However, the combine...
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| Publicado no: | Neurochem Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5801117/ https://ncbi.nlm.nih.gov/pubmed/28975464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-017-2411-9 |
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