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Vascular Protection to Increase the Safety of Tissue Plasminogen Activator for Stroke

Thrombolytic therapy with tissue plasminogen activator (tPA) remains the most effective treatment for acute ischemic stroke, but can cause vascular damage leading to edema formation and hemorrhagic transformation (HT). In this review, we discuss how tPA contributes to the pathogenesis of vascular da...

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Detalhes bibliográficos
Main Authors: Ishrat, Tauheed, Soliman, Sahar, Guan, Weihua, Saler, Mihaela, Fagan, Susan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602899/
https://ncbi.nlm.nih.gov/pubmed/22574982
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