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Repurposing an old drug to improve the safety and use of tissue plasminogen activator for acute ischemic stroke: Minocycline

There is only 1 US Food and Drug Administration-approved drug for acute ischemic stroke: tissue plasminogen activator (tPA). Due to a short time window and fear of intracerebral hemorrhage (ICH), tPA remains underutilized. There is great interest in developing combination drugs to use with tPA to im...

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Detalhes bibliográficos
Main Authors: Hess, David C, Fagan, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932486/
https://ncbi.nlm.nih.gov/pubmed/20575623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1592/phco.30.pt2.55S
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