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Minocycline Development for Acute Ischemic Stroke

Minocycline, a tetracycline antibiotic, has shown anti-inflammatory, anti-apoptotic, and neuroprotective effects in many models of cerebral ischemia and neurodegenerative disease. Its high penetration of the blood–brain barrier, good safety profile, and delayed therapeutic window make it an ideal ca...

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Detalhes bibliográficos
Main Authors: Fagan, Susan C., Cronic, Lydia E., Hess, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169090/
https://ncbi.nlm.nih.gov/pubmed/21909339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-011-0072-6
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