A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone

BACKGROUND: Multimeric naphthoquinones are redox-active compounds that exhibit antineoplastic, antiprotozoal, and antiviral activities. Due to their multimodal effect on perturbation of cellular oxidative state, these compounds hold great potential as therapeutic agents against highly proliferative...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:BMC Struct Biol
Päätekijät: Pidugu, Lakshmi Swarna Mukhi, Mbimba, J.C. Emmanuel, Ahmad, Muqeet, Pozharski, Edwin, Sausville, Edward A., Emadi, Ashkan, Toth, Eric A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730606/
https://ncbi.nlm.nih.gov/pubmed/26822308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12900-016-0052-x
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