A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone

BACKGROUND: Multimeric naphthoquinones are redox-active compounds that exhibit antineoplastic, antiprotozoal, and antiviral activities. Due to their multimodal effect on perturbation of cellular oxidative state, these compounds hold great potential as therapeutic agents against highly proliferative...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:BMC Struct Biol
Hlavní autoři: Pidugu, Lakshmi Swarna Mukhi, Mbimba, J.C. Emmanuel, Ahmad, Muqeet, Pozharski, Edwin, Sausville, Edward A., Emadi, Ashkan, Toth, Eric A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730606/
https://ncbi.nlm.nih.gov/pubmed/26822308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12900-016-0052-x
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky