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Overlapping signatures of chronic pain in the DNA methylation landscape of prefrontal cortex and peripheral T cells
We tested the hypothesis that epigenetic mechanisms in the brain and the immune system are associated with chronic pain. Genome-wide DNA methylation assessed in 9 months post nerve-injury (SNI) and Sham rats, in the prefrontal cortex (PFC) as well as in T cells revealed a vast difference in the DNA...
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| Publicat a: | Sci Rep |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4730199/ https://ncbi.nlm.nih.gov/pubmed/26817950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19615 |
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