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Overlapping signatures of chronic pain in the DNA methylation landscape of prefrontal cortex and peripheral T cells
We tested the hypothesis that epigenetic mechanisms in the brain and the immune system are associated with chronic pain. Genome-wide DNA methylation assessed in 9 months post nerve-injury (SNI) and Sham rats, in the prefrontal cortex (PFC) as well as in T cells revealed a vast difference in the DNA...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4730199/ https://ncbi.nlm.nih.gov/pubmed/26817950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19615 |
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