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Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease

The etiology of idiopathic Parkinson's disease (idPD) remains enigmatic despite recent successes in identification of genes (PARKs) that underlie familial PD. To find new keys to this incurable neurodegenerative disorder we focused on the poorly understood PARK14 disease locus (Pla2g6 gene) and...

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Pubblicato in:Nat Commun
Autori principali: Zhou, Qingde, Yen, Allen, Rymarczyk, Grzegorz, Asai, Hirohide, Trengrove, Chelsea, Aziz, Nadine, Kirber, Michael T., Mostoslavsky, Gustavo, Ikezu, Tsuneya, Wolozin, Benjamin, Bolotina, Victoria M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729940/
https://ncbi.nlm.nih.gov/pubmed/26755131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10332
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