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Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease

The etiology of idiopathic Parkinson's disease (idPD) remains enigmatic despite recent successes in identification of genes (PARKs) that underlie familial PD. To find new keys to this incurable neurodegenerative disorder we focused on the poorly understood PARK14 disease locus (Pla2g6 gene) and...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Zhou, Qingde, Yen, Allen, Rymarczyk, Grzegorz, Asai, Hirohide, Trengrove, Chelsea, Aziz, Nadine, Kirber, Michael T., Mostoslavsky, Gustavo, Ikezu, Tsuneya, Wolozin, Benjamin, Bolotina, Victoria M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729940/
https://ncbi.nlm.nih.gov/pubmed/26755131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10332
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