Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease

The etiology of idiopathic Parkinson's disease (idPD) remains enigmatic despite recent successes in identification of genes (PARKs) that underlie familial PD. To find new keys to this incurable neurodegenerative disorder we focused on the poorly understood PARK14 disease locus (Pla2g6 gene) and...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Zhou, Qingde, Yen, Allen, Rymarczyk, Grzegorz, Asai, Hirohide, Trengrove, Chelsea, Aziz, Nadine, Kirber, Michael T., Mostoslavsky, Gustavo, Ikezu, Tsuneya, Wolozin, Benjamin, Bolotina, Victoria M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729940/
https://ncbi.nlm.nih.gov/pubmed/26755131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10332
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