HIV-1 gp140 epitope recognition is influenced by immunoglobulin D(H) gene segment sequence

Complementarity determining region 3 of the immunoglobulin (Ig) H chain (CDR-H3) lies at the center of the antigen binding site where it often plays a decisive role in antigen recognition and binding. Amino acids encoded by the diversity (D(H)) gene segment are the main component of CDR-H3. Each D(H...

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Veröffentlicht in:Immunogenetics
Hauptverfasser: Wang, Yuge, Kapoor, Pratibha, Parks, Robert, Silva-Sanchez, Aaron, Alam, S. Munir, Verkoczy, Laurent, Liao, Hua-Xin, Zhuang, Yingxin, Burrows, Peter, Levinson, Michael, Elgavish, Ada, Cui, Xiangqin, Haynes, Barton F., Schroeder, Harry
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729650/
https://ncbi.nlm.nih.gov/pubmed/26687685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-015-0890-x
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