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Novel Wnt Regulator NEL-Like Molecule-1 Antagonizes Adipogenesis and Augments Osteogenesis Induced by Bone Morphogenetic Protein 2

The differentiation factor NEL-like molecule-1 (NELL-1) has been reported as osteoinductive in multiple in vivo preclinical models. Bone morphogenetic protein (BMP)-2 is used clinically for skeletal repair, but in vivo administration can induce abnormal, adipose-filled, poor-quality bone. We demonst...

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Xehetasun bibliografikoak
Argitaratua izan da:Am J Pathol
Egile Nagusiak: Shen, Jia, James, Aaron W., Zhang, Xinli, Pang, Shen, Zara, Janette N., Asatrian, Greg, Chiang, Michael, Lee, Min, Khadarian, Kevork, Nguyen, Alan, Lee, Kevin S., Siu, Ronald K., Tetradis, Sotirios, Ting, Kang, Soo, Chia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Investigative Pathology 2016
Gaiak:
Regular Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729267/
https://ncbi.nlm.nih.gov/pubmed/26772960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.10.011
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