High Doses of Bone Morphogenetic Protein 2 Induce Structurally Abnormal Bone and Inflammation In Vivo

The major Food and Drug Association–approved osteoinductive factors in wide clinical use are bone morphogenetic proteins (BMPs). Although BMPs can promote robust bone formation, they also induce adverse clinical effects, including cyst-like bone formation and significant soft tissue swelling. In thi...

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Detalhes bibliográficos
Main Authors: Zara, Janette N., Siu, Ronald K., Zhang, Xinli, Shen, Jia, Ngo, Richard, Lee, Min, Li, Weiming, Chiang, Michael, Chung, Jonguk, Kwak, Jinny, Wu, Benjamin M., Ting, Kang, Soo, Chia
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079169/
https://ncbi.nlm.nih.gov/pubmed/21247344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2010.0555
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