Novel Wnt Regulator NEL-Like Molecule-1 Antagonizes Adipogenesis and Augments Osteogenesis Induced by Bone Morphogenetic Protein 2

The differentiation factor NEL-like molecule-1 (NELL-1) has been reported as osteoinductive in multiple in vivo preclinical models. Bone morphogenetic protein (BMP)-2 is used clinically for skeletal repair, but in vivo administration can induce abnormal, adipose-filled, poor-quality bone. We demonst...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Am J Pathol
Päätekijät: Shen, Jia, James, Aaron W., Zhang, Xinli, Pang, Shen, Zara, Janette N., Asatrian, Greg, Chiang, Michael, Lee, Min, Khadarian, Kevork, Nguyen, Alan, Lee, Kevin S., Siu, Ronald K., Tetradis, Sotirios, Ting, Kang, Soo, Chia
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Investigative Pathology 2016
Aiheet:
Regular Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729267/
https://ncbi.nlm.nih.gov/pubmed/26772960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.10.011
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