Novel Wnt Regulator NEL-Like Molecule-1 Antagonizes Adipogenesis and Augments Osteogenesis Induced by Bone Morphogenetic Protein 2

The differentiation factor NEL-like molecule-1 (NELL-1) has been reported as osteoinductive in multiple in vivo preclinical models. Bone morphogenetic protein (BMP)-2 is used clinically for skeletal repair, but in vivo administration can induce abnormal, adipose-filled, poor-quality bone. We demonst...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Am J Pathol
Hauptverfasser: Shen, Jia, James, Aaron W., Zhang, Xinli, Pang, Shen, Zara, Janette N., Asatrian, Greg, Chiang, Michael, Lee, Min, Khadarian, Kevork, Nguyen, Alan, Lee, Kevin S., Siu, Ronald K., Tetradis, Sotirios, Ting, Kang, Soo, Chia
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2016
Schlagworte:
Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729267/
https://ncbi.nlm.nih.gov/pubmed/26772960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.10.011
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge