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Exploring Reovirus Plasticity for Improving Its Use as Oncolytic Virus

Reoviruses are non-enveloped viruses with a segmented double stranded RNA genome. In humans, they are not associated with serious disease. Human reoviruses exhibit an inherent preference to replicate in tumor cells, which makes them ideally suited for use in oncolytic virotherapies. Their use as ant...

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Vydáno v:Viruses
Hlavní autoři: Kemp, Vera, Hoeben, Rob C., van den Wollenberg, Diana J. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728564/
https://ncbi.nlm.nih.gov/pubmed/26712782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8010004
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