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Exploring Reovirus Plasticity for Improving Its Use as Oncolytic Virus

Reoviruses are non-enveloped viruses with a segmented double stranded RNA genome. In humans, they are not associated with serious disease. Human reoviruses exhibit an inherent preference to replicate in tumor cells, which makes them ideally suited for use in oncolytic virotherapies. Their use as ant...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Viruses
Главные авторы: Kemp, Vera, Hoeben, Rob C., van den Wollenberg, Diana J. M.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728564/
https://ncbi.nlm.nih.gov/pubmed/26712782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8010004
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