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Exploring Reovirus Plasticity for Improving Its Use as Oncolytic Virus

Reoviruses are non-enveloped viruses with a segmented double stranded RNA genome. In humans, they are not associated with serious disease. Human reoviruses exhibit an inherent preference to replicate in tumor cells, which makes them ideally suited for use in oncolytic virotherapies. Their use as ant...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Kemp, Vera, Hoeben, Rob C., van den Wollenberg, Diana J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728564/
https://ncbi.nlm.nih.gov/pubmed/26712782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8010004
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