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Oncolytic Reovirus Infection Is Facilitated by the Autophagic Machinery

Mammalian reovirus is a double-stranded RNA virus that selectively infects and lyses transformed cells, making it an attractive oncolytic agent. Despite clinical evidence for anti-tumor activity, its efficacy as a stand-alone therapy remains to be improved. The success of future trials can be greatl...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Kemp, Vera, Dautzenberg, Iris J. C., Limpens, Ronald W., van den Wollenberg, Diana J. M., Hoeben, Rob C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691618/
https://ncbi.nlm.nih.gov/pubmed/28934149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v9100266
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