Massively parallel cis-regulatory analysis in the mammalian central nervous system

Cis-regulatory elements (CREs, e.g., promoters and enhancers) regulate gene expression, and variants within CREs can modulate disease risk. Next-generation sequencing has enabled the rapid generation of genomic data that predict the locations of CREs, but a bottleneck lies in functionally interpreti...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genome Res
Main Authors: Shen, Susan Q., Myers, Connie A., Hughes, Andrew E.O., Byrne, Leah C., Flannery, John G., Corbo, Joseph C.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2016
Teme:
Method
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728376/
https://ncbi.nlm.nih.gov/pubmed/26576614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.193789.115
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