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A massively parallel reporter assay reveals context-dependent activity of homeodomain binding sites in vivo
Cone-rod homeobox (CRX) is a paired-like homeodomain transcription factor (TF) and a master regulator of photoreceptor development in vertebrates. The in vitro DNA binding preferences of CRX have been described in detail, but the degree to which in vitro binding affinity is correlated with in vivo e...
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| Опубликовано в: : | Genome Res |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6169884/ https://ncbi.nlm.nih.gov/pubmed/30158147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.231886.117 |
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