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Massively parallel synthetic promoter assays reveal the in vivo effects of binding site variants
Gene promoters typically contain multiple transcription factor binding sites (TFBSs), which may vary in affinity for their cognate transcription factors (TFs). One major challenge in studying cis-regulation is to understand how TFBS variants affect gene expression. We studied the in vivo effects of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3814890/ https://ncbi.nlm.nih.gov/pubmed/23921661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.157891.113 |
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