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Massively parallel cis-regulatory analysis in the mammalian central nervous system
Cis-regulatory elements (CREs, e.g., promoters and enhancers) regulate gene expression, and variants within CREs can modulate disease risk. Next-generation sequencing has enabled the rapid generation of genomic data that predict the locations of CREs, but a bottleneck lies in functionally interpreti...
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發表在: | Genome Res |
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Main Authors: | , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Cold Spring Harbor Laboratory Press
2016
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4728376/ https://ncbi.nlm.nih.gov/pubmed/26576614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.193789.115 |
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