EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos

The extent to which histone modifying enzymes contribute to DNA methylation in mammals remains unclear. Previous studies suggested a link between the lysine methyltransferase EHMT2 (also known as G9A and KMT1C) and DNA methylation in the mouse. Here, we used a model of knockout mice to explore the r...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Auclair, Ghislain, Borgel, Julie, Sanz, Lionel A., Vallet, Judith, Guibert, Sylvain, Dumas, Michael, Cavelier, Patricia, Girardot, Michael, Forné, Thierry, Feil, Robert, Weber, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728372/
https://ncbi.nlm.nih.gov/pubmed/26576615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.198291.115
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